Mashhad UMS Pits Smart Nanocarriers against Leukemia

Wednesday, June 17, 2015 - 11:34

Iranian researchers have succeeded in synthesizing a drug transfer system which has proven to be effective in targeted treatment of Leukemia in vitro. This biocompatible system has a controlled, long-acting release process.

635699586940137774 Leukemia is the most common cancer of the blood cells. It usually begins in the bone marrow, which makes white and red blood cell, and platelets. In people with leukemia, the bone marrow produces abnormal white blood cells, called leukemia cells. At first, leukemia cells function almost normally. But over time, as more leukemia cells are produced, they may crowd out the healthy blood cells. This makes it difficult for the blood to carry out its normal functions. Daunorubicin or daunomycin (daunomycin cerubidine) is the chemotherapeutic drug of choice from the Anthracycline family that is widely used as a treatment for this type of cancer. Dr. Khalil Abnous, faculty member of Mashhad University of Medical Sciences, stated that in order to facilitate the transportation of Daunorubicin, Aptamer-gold nano particles were used in this investigation. This system can effectively reduce Daunorubicin side effects and increase its effectiveness. This research was spearheaded by a team supervised by Dr. Khalil Abnous and Dr. Mohammad Taghdisi Heidarian, faculty members of Mashhad University of Medical Sciences.



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