Iranian Researchers Use Nanotechnology to Accelerate Wound Healing

Sunday, June 2, 2019 - 15:47

Researchers of Amirkabir University of Technology can speed up wound healing process through extracting cellulose nanocrystals (CNCs) from waste cotton stalks and then incorporated into electrospun gelatin nanofibers.

According to an ISCA report, Ahmad Hivechi in collaboration with Hajir Bahrami in Amirkabir University of Technology have succeeded in speeding up wound healing process through extracting cellulose nanocrystals (CNCs) from waste cotton stalks and then incorporated into electrospun gelatin nanofibers.

As hivenchi explained, the results were nanocomposites that may speed up wound healing process, yet further studies are needed before making a firm conclusion. According to Hivechi, the resulted nanofibers can be directly used as a dressing for wounds, or it can be incorporated into sterile gauze.

“The advantage of this wound dressing material, over other materials, is that it has a high rate of biodegradability. It means that the dressing material would be quicker in absorbing into the skin,” said Hivechi. The material contains Polycaprolactone (PCL) that is a highly biodegradable polyester, he added.

“The research so far has showed that the material increases cell adhesion and cell growth rate. When tested on lab rats, the wounds that had not been healed in 14 days, got healed in seven days. However, we need to do tests on bigger animals, and then human, before making any conclusion,” he declared.

“We used the waste stalks of cotton harvested in Golestan province; Golestan used to be among the biggest suppliers of cotton in the country, but unfortunately the production has decreased,” said Hivechi who himself was born in Golestan.

Parts of this research, including cell culture, drug delivery and modeling were done in University of Minnesota in collaboration with Professor Ronald A. Siegel. The in vivo tests were carried out in Iran University of Medical Sciences in collaboration with Dr. Peiman Brouki Milan.

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