Science & Research IAU Researchers Can Heal Diabetes Wounds with Cold Plasma

Sunday, December 1, 2019 - 11:40

Researchers of Science and Research Islamic Azad University have created atmospheric cold plasma device which can heal diabetic wound.

In her interview with ISCA News Agency, Sara Fathollah, S & R IAU student of Mechanical Engineering; also the head of “Hoopad Plasma Industry Co.” stated that as the company’s most recent product, cold plasma device can be applied for diabetes wound management.

Based on an article, released in Nature by Fathollah, the aim of this study is to present a non-thermal atmospheric plasma treatment as a novel therapy for diabetic wounds.

She noted that the device, made domestically with reasonable expenses in comparison with its foreign samples, has been reached to the commercialization as well as the industrialization phase which is now available in diabetes treatment centers.

According to the study, “the plasma consists of ionized helium gas that is produced by a high-voltage (8 kV) and high-frequency (6 kHz) power supply. Diabetes was induced in rats via an intravascular injection of streptozotocin.

“The plasma was then introduced to artificial xerograph wounds in the rats for 10 minutes. Immunohistochemistry assays were performed to determine the level of transforming growth factor (TGF-β1) cytokine.

“The results showed a low healing rate in the diabetic wounds compared with the wound-healing rate in non-diabetic animals (P < 0.05). Moreover, the results noted that plasma enhanced the wound-healing rate in the non-diabetic rats (P < 0.05) and significant wound contraction occurred after the plasma treatment compared with untreated diabetic wounds (P < 0.05).

“Histological analyses revealed the formation of an epidermis layer, neovascularization and cell proliferation. The plasma treatment also resulted in the release of TGF-β1 cytokine from cells in the tissue medium. The findings of this study demonstrate the effect of plasma treatment for wound healing in diabetic rats.”


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