Scientists Can Repair Damaged Blood Vessels Using ‘Human Textiles’

Wednesday, February 12, 2020 - 14:51

A team of researchers from France have succeeded in creating a “human textile” that could add a significant tool to the tissue repair arsenal.

According to the Medical Life Science report, this is the challenge set by Inserm researcher Nicolas L'Heureux, who is working on the human extracellular matrix - the structural support of human tissues that is found around practically all of the body's cells.

In a study published in Acta Biomaterialia, L'Heureux and his colleagues at the Tissue Bioengineering unit (Inserm/Université de Bordeaux) describe how they have cultivated human cells in the laboratory to obtain extracellular matrix deposits high in collagen - a structural protein that constitutes the mechanical scaffold of the human extracellular matrix.

"We have obtained thin but highly robust extracellular matrix sheets that can be used as a construction material to replace blood vessels," said Nicolas L'Heureux, Inserm researcher.

“By combining this truly “bio” material with a textile-based assembly, this original tissue engineering approach is highly versatile and can produce a variety of strong human textiles that can be readily integrated in the body,” co-author and Inserm researcher L’Heureux said in a press release.

“This novel strategy holds the promise of a next generation of medical textiles that will be mechanically strong without any foreign scaffolding, and will have the ability to truly integrate into the host’s body,” researchers concluded.


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